Start date: As soon as possible

Department: Cytogenetics Laboratory

Reports To: Cytogenetic Laboratory Manager

Experience: 1-3 years

Type of position: Full time, Permanent (40 h/week)

Salary: $50,000-60,000 (commensurate with experience) + Benefits (Health insurance)

Paid time off: 20 days per year + public holidays

Location: Research Triangle Park, Durham, NC

COMPANY

Stem Genomics is a biotechnology company based in Durham, North Carolina and Montpellier, France. By offering innovative tests, Stem Genomics has become a leader in the quality control of cells for research and therapy. We provide biotech/pharma and academic laboratories with specific services and kits to assess the genetic integrity of cells. Our flagship tests use digital PCR, karyotyping, and NGS sequencing to detect genetic abnormalities in stem cells and other cells for therapeutic purposes. As a one-stop shop, Stem Genomics also offers a range of tests to support the research and development of cell therapies (www.stemgenomics.com). Stem Genomics and KaryoLogic are now part of the same company.

To support its strong growth in North America, Stem Genomics Inc. is expanding its Cytogenetics team by creating the new role of Cytogenetic Technologist to support its testing platform in the Raleigh-Durham Research Triangle.

JOB DESCRIPTION

The Cytogenetic Technologist is a mid to entry-level position responsible for performing routine cytogenetic procedures under supervision. This role involves processing live and cryopreserved cell lines (human and non-human iPSCs, ESCs, tumor-derived) for chromosome analysis, fluorescence in situ hybridization (FISH), and related techniques to aid in the assessment of genetic integrity and genomic characterization. The technologist ensures accurate, timely, and high-quality results while adhering to laboratory protocols, safety standards, and good laboratory practice (GLP).

This position is ideal for individuals with foundational knowledge in cytogenetics seeking hands-on experience in a quality testing R&D lab setting.

KEY RESPONSIBILITIES

• Specimen Processing and Culture: Receive, log, and prepare specimens. Initiate and maintain cell cultures (e.g., cryopreserved cells, live/active cultures) using sterile techniques. Perform harvests, feeds and subcultures as needed.

• Slide Preparation and Staining: Harvest cells, prepare slides, and apply banding techniques (e.g., G-banding). Monitor and adjust for quality.

• Microscopic Analysis: Perform microscopic examination of chromosomes, identify numerical and structural abnormalities, and prepare karyotypes using image capture and karyotyping software (Leica CytoVision or similar).

• FISH and Advanced Techniques: Assist with or perform FISH processing, hybridization, washing, and analysis (metaphase/interphase) under supervision.

• Documentation and Reporting: Accurately document procedures, results, and quality control. Use International System for Human Cytogenetic Nomenclature (ISCN). Generate preliminary reports for review by a cytogeneticist. Maintain records for traceability and compliance.

• Quality Assurance: Participate in daily QA/QC, reagent checks, equipment maintenance, and proficiency testing. Troubleshoot basic technical issues and refer complex problems to senior staff.

• Safety and Compliance: Follow universal precautions, biosafety protocols, and laboratory policies. Participate in inspections and continuing education.

• Additional Duties: Assist with inventory, orientation of new staff, and implementation of new methodologies as assigned.

QUALIFICATIONS AND REQUIREMENTS

Education:

• Bachelor’s degree in Biological Sciences, Clinical Laboratory Science, Genetics, or a related field (or equivalent with sufficient science coursework).

Certification/Licensure:

• Eligible for or holds certification as Technologist in Cytogenetics (CG(ASCP)) or equivalent preferred.

Experience:

• 1–3 years of cytogenetics laboratory experience.

Knowledge, Skills, and Abilities:

• Strong understanding of human chromosomes, cytogenetic techniques, and common abnormalities associated with genetic disorders and neoplasms.

• Excellent manual dexterity, pattern recognition, attention to detail, and visual acuity for microscopic work.

• Ability to work independently with guidance, manage multiple tasks, and meet strict turnaround times.

• Proficient computer skills (laboratory information systems, karyotyping software, Microsoft Office).

• Effective communication and interpersonal skills for collaborating with team members and managers.

• Commitment to quality, safety, and ethical standards in a high-complexity lab environment.

Physical and Work Environment:

• Ability to stand for extended periods, handle biohazardous materials, and lift up to 25 lbs occasionally.

• Exposure to laboratory chemicals, specimens, and moderate noise levels. Use of PPE required.

• Some weekend/holiday rotation possible.

This job description is not exhaustive and may be modified as needed to meet laboratory demands. Equal Opportunity Employer.

PROCEDURE

Please send your resume and cover letter by email to [email protected].

SCHEDULE

Receipt of applications and interview of candidates: On a rolling basis