Manufacturing Technician II (Durham, NC, US)

Oxford Biomedica
Oxford Biomedica

Durham, NC, USA

Posted on Sep 23, 2026

Join Us in Changing Lives

At OXB, our people are at the heart of everything we do. We’re on a mission to enable life-changing therapies to reach patients around the world—and we’re looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful.

Following the expansion of our US footprint with the acquisition of a new commercial-scale viral vector facility in Durham, North Carolina we have some new opportunities to join us.

We’re currently recruiting for a Manufacturing Technician II to join our Manufacturing team. In this role, you will you will contribute to the buildout and qualification of new manufacturing suites for viral vectors and vaccines, establishing state-of-the-art manufacturing operation, playing a key part in advancing our mission and making a real difference.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the United States.

Your responsibilities in this role would be to:

  • Assist with startup activities within area of responsibility.
  • Support commissioning and qualification of production equipment.
  • Contribute to the review and creation of operational documents by providing technical input.
  • Operate on the manufacturing floor in compliance with cGMP and standard operating procedures (SOPs).
  • Prepare equipment for manufacturing operations and monitor performance to ensure process specifications are met.
  • Use and maintain benchtop equipment in accordance with relevant procedures.
  • Demonstrate a solid understanding of cGMP principles and apply them to daily responsibilities.
  • Follow accurate written and verbal procedures when operating production equipment and performing processing steps.
  • Maintain cleanliness and orderliness of the process area.
  • Practice safe work habits and adhere to all safety procedures and guidelines.
  • Assist in the training and onboarding of new and junior staff.

We are looking for:

  • High School Diploma/GED and 2+ years in cGMP manufacturing environment or Bachelor’s degree and 2+ years experience
  • Ability to lift a minimum of 40 lbs.
  • Ability to stand for 6 hours in a production suite
  • Ability to gown and gain entry to manufacturing areas
  • Ability to work weekends, including holidays as scheduled

About Us:

OXB (LSE: OXB) is a global quality and innovation-led contract development and manufacturing organisation (CDMO) in cell and gene therapy with a mission to enable its clients to deliver life changing therapies to patients around the world.

One of the original pioneers in cell and gene therapy, OXB has 30 years of experience in viral vectors; the driving force behind the majority of cell and gene therapies. OXB collaborates with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV), adenovirus and other viral vector types. OXB’s world-class capabilities range from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.

OXB offers a vast number of technologies for viral vector manufacturing, including a 4th generation lentiviral vector system (the TetraVecta™ system), a dual-plasmid system for AAV production, suspension and perfusion process using process enhancers and stable producer and packaging cell lines.

OXB, a FTSE250 and FTSE4Good constituent, is headquartered in Oxford, UK. It has development and manufacturing facilities across Oxfordshire, UK, Lyon and Strasbourg, France, Bedford MA, and Durham NC, US.

Why Join Us?

  • 💸 Competitive total reward packages
  • 🧘 Wellbeing programs that support your mental and physical health
  • 🚀 Career development opportunities to help you grow and thrive
  • 🤝 Supportive, inclusive, and collaborative culture
  • 🧪 State-of-the-art labs and manufacturing facilities
  • 🌍 A company that lives its values: Responsible, Responsive, Resilient, Respect

We want you to feel inspired every day. At OXB, we’re future-focused and growing fast. We succeed together—through passion, commitment, and teamwork.

Ready to Make a Difference?