Clinical Laboratory Technologist IV - 2nd shift, Sun-Wed (1:30pm-12am) # 4453
Grail
Durham, NC, USA
USD 27.88-32.69 / hour
Posted on Dec 16, 2025
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
GRAIL is headquartered in Menlo Park, California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
For more information, please visit grail.com.
The Clinical Laboratory Technologist IV is responsible for performing high complexity laboratory testing on patient specimens, performing quality control and quality assurance procedures and complying with all applicable local, state and federal laboratory requirements. The work requires maintaining meticulous and organized records, excellent attention to detail, the ability to multitask, be flexible with tasks and schedules and the ability to work independently in a team environment.
This position works on-site full-time at our office located in Durham, NC.
This CLT IV position works Sun-Wed 2nd shift (1:30pm-12am)
Responsibilities:
- Perform tasks which require the exercise of independent judgment and responsibility, with minimal supervision by the director or supervisor.
- Perform pre-analytical and analytical procedures including testing, quality control, preparation and aliquoting of reagents, analyses, and maintain records of tests according to the laboratory’s standard operating procedures.
- Maintaining records that demonstrate proficiency testing samples are tested in the same manner as patient specimens.
- Adhere to laboratory’s quality assurance procedures, including documenting all:
- Quality control activities
- Instrument and equipment verifications
- Maintenance and preventive maintenance
- Follow the laboratory’s policies and procedures whenever test systems are not within the laboratory’s established performance specifications.
- Identify and document problems that may adversely affect test performance and notifying the supervisor, assistant director, or director.
- Document all corrective actions taken when test systems deviate from the laboratory’s established performance specifications.
- Operate and maintain laboratory instruments and equipment according to laboratory standard operating procedures.
- Troubleshoot and problem solve minor instrument issues.
- Check and record temperature and instrument status or initiate a service request as necessary.
- Review, and interpret patient data as assigned.
- Perform and document reagent qualifications per the approved protocols.
- Perform and document routine preventive maintenance.
- Report all concerns of test quality and/or safety to the Laboratory Supervisor/Manager or Safety Officer.
- Communicate effectively with coworkers and non-laboratory personnel.
- Identify process improvement opportunities and report to laboratory management.
- Provide updates to Laboratory Supervisors/Leads regarding any issues.
- Monitor data and process status as needed.
- Participate in daily, weekly and monthly laboratory cleanliness activities/procedures.
- Independently identify and troubleshoot minor problems that adversely affect the test performance.
- Perform other laboratory duties as needed.
Preferred Qualifications:
- Bachelor’s degree in medical technology or laboratory science from an accredited institution OR
- Bachelor’s degree in one of the chemical, physical, or biological sciences from an accredited institution and at least 6 months of acceptable supervised experience and/or relevant training
- 2 + years of Clinical lab testing experience
- Experience in molecular biology techniques preferred
- Working knowledge of local, state and federal laboratory regulations preferred
- Able to integrate and apply feedback in a professional manner
- Able to prioritize and drive to results with a high emphasis on quality
- Ability to work as part of a team within a highly collaborative environment
- Strong computer skills
- Ability to analyze and solve basic issues that impact the performance of the assay
- Ability to proactively communicate consistently, clearly and honestly
- Ability to prioritize tasks with a high emphasis on quality
- Ability to participate in projects and complete assignments as expected
- Flexibility of work schedule to meet the needs of GRAIL’s Clinical Laboratory
Physical Demands and Work Environment:
- Hours and days may vary depending on operational needs
- Standing or sitting for long periods of time may be necessary
- May be exposed to hazardous materials, blood specimens and instruments with moving parts, heating or freezing elements, and high speed centrifugation
- Repetitive manual pipetting may be necessary
- Some lifting (up to 25 pounds) may be necessary
The expected, full-time, hourly base pay scale for this position is $27.88 - 32.69/ hour. Actual base pay will consider skills, experience, and location.
Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time. In addition, GRAIL offers a competitive benefit package, including flexible time-off, a 401(k) with a company % match, medical, dental, and vision insurance plans, and carefully selected mindfulness offerings, in accordance with our applicable plans and policies.
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. It is GRAIL policy to provide equal employment opportunities without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, marital status, protected veteran status, disability status, medical condition, or any other class or characteristic protected by applicable federal, state, and local laws. This policy applies to all phases of employment, including, but not limited to: recruiting, hiring, training, promotion, and termination at all levels of employment. GRAIL maintains a drug-free workplace.
Additionally, GRAIL will consider all qualified job-seekers with criminal histories in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.
We welcome job-seekers from all backgrounds to join us!