AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease. AskBio’s gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing.

Our vision: Pioneering science to create transformative molecular medicines.

Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.

Our principles:

• Advance innovative science by pushing boundaries.

• Bring transformative therapeutics to patients in need.

• Provide an environment for employees to reach their fullest potential.

Our values:

• Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.

• Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.

• Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.

• Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.

• Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

Position Summary

As the Director of Portfolio Strategy at AskBio, you will play a pivotal role in shaping the future of our portfolio through strategic leadership and innovative thinking. This position offers a unique opportunity to lead the development and execution of a comprehensive portfolio strategy that integrates scientific, clinical, commercial, and financial perspectives. You will work closely with cross-functional teams, providing strategic insights that drive investment decisions and ensure alignment with our corporate goals.

In this dynamic role, you will facilitate governance processes and scenario planning, enabling effective portfolio reviews that enhance our decision-making capabilities. Your expertise will be crucial in building robust portfolio models in partnership with Finance and Program Leadership, supporting critical discussions on resource allocation and trade-offs. You will collaborate with R&D, Program Management, Technical Operations, and Regulatory teams to monitor program progress and assess risks, ensuring that our portfolio remains competitive and aligned with market needs.

This position not only allows you to influence our strategic direction but also offers the chance to lead long-range planning and communication with the Executive Leadership Team. As a strategic thought partner to senior leaders, you will help drive initiatives that enhance our portfolio analytics and decision-support tools, ultimately supporting the growth and success of our company.

Job Responsibilities

• Lead the development and execution of portfolio strategy, integrating scientific, clinical, commercial, and financial perspectives

• Facilitate portfolio governance processes, scenario planning, and cross-functional portfolio reviews

• Provide strategic insights to guide asset-level and portfolio-level investment decisions

• Partner with Finance and Program Leadership to build portfolio models that support valuation, resource allocation, and trade-off discussions.\Collaborate with R&D, Program Management, Technical Operations, and Regulatory to track and assess program progress, risks, and dependencies

• Lead long-range planning exercises, strategic planning cycles, and communications to the Executive Leadership Team

• Serve as a strategic thought partner for the Head of Strategy and other senior leaders

• Develop and continuously improve portfolio analytics, dashboards, and decision-support tools

• Support strategic initiatives and special projects as needed (e.g., platform prioritization, organizational design, strategic due diligence)

Minimum Requirements

• Master’s Degree in life sciences, business, or a related field

• 10+ years of progressive experience in portfolio strategy, corporate development, or strategic planning within the biotechnology or pharmaceutical industry

• Strong understanding of gene therapy and related markets, with proven ability to assess scientific, clinical and business potential

Preferred Education, Experience and Skills

• Exceptional strategic thinking, analytical, and financial modeling skills

• Strong program management and facilitation skills

• Excellent communication and relationship-building capabilities

• Experience leading cross-functional teams in the biotech or pharma environment

• Emerging understanding and strong learning ability of technology platforms such as small molecules, biologics, or gene and cell therapy

• Knowledge of disease pathobiology, standard of care, and unmet medical needs in core therapeutic areas

• Business acumen and learning agility for the end-to-end drug development process

• Entrepreneurial mindset and the courage to challenge the status quo

• Ability to thrive in a fast-paced, dynamic environment, driving results through collaboration

• Strong leadership and collaboration skills, with a focus on self-development, peer development, and strategic influencing

AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at careers@askbio.com.

Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency.